Daria Mochly-Rosen, Ph.D.
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Steve F. Dowdy, Ph.D. |
Ronald Burch, M.D. Ph.D.
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Peter A. Kiener, D. Phil |
Richard D. DiMarchi, Ph.D.
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Daria Mochly-Rosen, Ph.D.
Founder and Chair of the SAB
Dr. Daria Mochly-Rosen received her B.Sc. in Biological Sciences from Tel
Aviv University and her doctorate in Chemical Immunology from the Weizmann
Institute of Science in Rehovot. She joined the Stanford University faculty
in 1993. Dr. Mochly-Rosen is a Professor in the Department of Molecular Pharmacology,
and Professor, by courtesy, in the Department of Neurosurgery at Stanford University
School of Medicine. From 2002-2006, she was the Chair of the Department
of Molecular Pharmacology. In 2005, she became the Senior Associate Dean for
Research for Stanford University School of Medicine. Dr. Mochly-Rosen was the
Reed-Hodgson Professor in Human Biology at Stanford from 1996 to 2001 and was
appointed the inaugural holder of the George D. Smith Professorship in Translational
Medicine in 2003. She currently leads the school’s effort in advancing
the field of molecular pharmacology and chemical biology and its application
to translational medicine. A biochemist by training, Dr. Mochly-Rosen
is focused on medical research. She studies a family of enzymes called
protein kinase C, which, when activated, regulate diverse functions such as
heart rate, the response of the heart and brain to stress induced by heart
attack, and the regulation of cell growth in normal and cancer tissues. Her
laboratory generated novel isozyme-specific inhibitors and activators. This
research led to the foundation of KAI Pharmaceuticals Inc.
Ronald Burch, M.D. Ph.D
Dr. Burch received a Ph.D. in Pharmacology and M.D. from the Medical University of South
Carolina and served as a Medical Staff Fellow at the Nationals Institutes of Health in the
Laboratory of Julius Axelrod, NL. Ron has worked within the pharmaceutical industry for more
than 20 years: at Nova Pharmaceuticals as Director, Pain & Inflammation; Rhone Poulenc Rorer
as Director Immunology and Bone Metabolism; Zeneca Pharmaceuticals as Director, Pharmacology
(CNS, Pulmonary and Renal) and Worldwide Head, CNS Therapeutic Area Team; Purdue Pharma as Vice
President Scientific Evaluations & Immunotherapeutics and as founder of Purdue BioPharma LP.
Ron founded AlgoRx Pharmaceuticals and served as CEO until its merger with Corgentech to form
Anesiva. Currently Ron serves on the Board of Directors of Biowave Corp and as Chief Medical
Officer of Pacira Pharmaceuticals.
Richard D. DiMarchi, Ph.D.
Dr. DiMarchi is the Linda & Jack Gill Chair in Biomolecular Sciences and
Professor of Chemistry at Indiana University. He is a retired Group Vice President
at Eli Lilly & Company where for more than two decades he provided leadership
for biotechnology, endocrine research and product development. He is a co-founder
of the biotechnology companies Ambrx and Inproteo. He previously served as
a board member of both the biotechnology trade group BIO and of Millennium
Biotherapeutics. His current scientific activities remain focused on the relationship
of protein structure and function, with a particular interest in novel methods
of macromolecular synthesis and drug delivery. He contributed to the discovery
of Humalog® and commercial development of Humulin®, Humatrope®, Glucagon®,
Xigris®, Forteo®, and Evista®. Humalog® represents the first biosynthetic hormone
optimized by rDNA technology approved as a human medicine and presently registers
annual sales in excess of one billon US dollars.
Steve F. Dowdy, Ph.D.
Dr. Dowdy is an Investigator of the Howard Hughes Medical Institute (HHMI)
and Professor of Cellular & Molecular Medicine at the University of California,
San Diego (UCSD) School of Medicine. He received his Ph.D. from the University
of California, Irvine, where he studied with Dr. Eric Stanbridge. He did his
postdoctoral work with Dr. Robert Weinberg at the Whitehead Institute, Massachusetts
Institute of Technology. Previously, he was an Assistant Investigator of HHMI
and Assistant Professor of Pathology and Medicine at Washington University
School of Medicine. His research has revolved around understanding the molecular
basis of G1 cell cycle progression, how it is deregulated during oncogenesis
and the delivery of experimental anticancer macromolecular therapeutics through
protein transduction domains.
Peter A. Kiener, D. Phil
Dr. Peter Kiener is currently the Executive Vice President, Research and Development at MedImmune Inc, which is a subsidiary of AstraZeneca PLC. In this role Dr Kiener has global responsibility for the development of the biologics portfolio for the company. Dr. Kiener holds a bachelor of science degree with honors in chemistry from Lancaster University, Lancaster, UK, and a doctorate of philosophy in biochemistry from the Sir William Dunn School of Pathology, Oxford University, Oxford, UK. Prior to joining MedImmune, Dr. Kiener spent 18 years with Bristol-Myers Squibb’s (BMS) Pharmaceutical Research Division, finally holding the position of Director, Immunology, Inflammation, Pulmonary and Oncology Drug Discovery at the BMS facility in Princeton, New Jersey. Before his employment at Bristol-Myers, Dr. Kiener previously served as Assistant Professor at the University of North Texas/Texas College of Osteopathic Medicine’s Department of Anatomy; as a Research Associate at the Department of Biochemistry, University of Massachusetts (Amherst); and as a Postdoctoral Research Assistant, Medical Research Council, Sir William Dunn School of Pathology, University of Oxford. Dr Kiener has more than 100 publications in peer-reviewed journals and is an inventor on six issued patents and 10 published patents, he also serves as a member of the Board of Directors on two biotechnology companies, Virdante and Synovex.
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